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. 2016 Dec 30;4(24):e13057. doi: 10.14814/phy2.13057

Figure 4.

Figure 4

Impact of BAFFR‐Fc treatment on lung and spleen B‐ and T‐cell populations. (A) Female BALB/c mice were exposed to room air (open bars) or cigarette smoke (solid bars) for 24 weeks. BAFFR‐Fc or isotype control was administered intraperitoneally twice a week over the last 12 weeks of cigarette smoke exposure. (B) Female BALB/c mice were exposed to room air (open bars) or cigarette smoke (black bars) for 24 weeks. Following smoking cessation, BAFFR‐Fc or isotype control was administered intraperitoneally for 4 weeks prior to killing. Single‐cell suspensions from the lungs and spleens were analyzed by flow cytometry. Data show B cells, CD4 T cells, and CD8 T cells as percent of the total singlets (mean ± SEM, n = 5/group). Bars with different superscripts are significantly different from each other and bars with the same superscript do not differ significantly.