Table 2.
Baseline Information of Replication Cohort
| Variable | All Patients (n=646) | With MACCE (n=80) | Without MACCE (n=566) | P Value |
|---|---|---|---|---|
| Age, y | 62.54 (±6.85) | 63.73 (±7.12) | 62.38 (±6.80) | 0.099 |
| Female sex | 79 (12.2) | 11 (13.8) | 68 (12.0) | 0.657 |
| BMI, kg/m2 | 26.83 (±3.21) | 27.32 (±3.46) | 26.76 (±3.17) | 0.144 |
| Smokers | 447 (69.2) | 56 (70.0) | 391 (69.1) | 0.868 |
| Hypertension | 430 (66.6) | 51 (63.7) | 379 (67.0) | 0.569 |
| Diabetes mellitus | 327 (50.6) | 36 (45.0) | 291 (51.4) | 0.283 |
| Insulin‐treated diabetes mellitus | 34 (5.3) | 4 (5.0) | 30 (5.3) | 1 |
| Renal dysfunction | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 |
| COPD | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 |
| Peripheral arterial disease | 29 (4.5) | 5 (6.3) | 24 (4.2) | 0.416 |
| Previous MI | 512 (79.3) | 67 (83.8) | 445 (78.6) | 0.29 |
| Previous PCI | 125 (19.3) | 16 (20.0) | 109 (19.3) | 0.875 |
| Aspirin | 609 (94.3) | 71 (88.8) | 538 (95.1) | 0.023a |
| ACE inhibitor | 162 (25.1) | 23 (28.7) | 139 (24.6) | 0.418 |
| β‐blocker | 470 (72.8) | 56 (70.0) | 414 (73.1) | 0.554 |
| Diuretics | 71 (11.0) | 15 (18.8) | 56 (9.9) | 0.018a |
| Calcium‐channel blocker | 210 (32.5) | 26 (32.5) | 184 (32.5) | 0.999 |
| Statins | 433 (67.0) | 42 (52.5) | 391 (69.1) | 0.003a |
Values are presented as numbers of patients or means±SD. ACE indicates angiotensin‐converting enzyme; BMI, body mass index; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; MACCE, major adverse cardiac and cerebrovascular events.
a
Statistically significant (P<0.05).