Table 2.
Clinical and Lesion Characteristics According to WSS Groups
| Low (n=55) | Intermediate (n=54) | High (n=54) | P Value | |
|---|---|---|---|---|
| Age, y | 62.1±7.6 | 61.7±10.2 | 62.9±8.9 | 0.758 |
| Male | 36 (65.5) | 43 (79.6) | 40 (74.1) | 0.244 |
| BSA | 1.9±0.3 | 1.9±0.2 | 1.9±0.2 | 0.457 |
| Race (white) | 40 (72.7) | 40 (74.1) | 36 (66.7) | 0.784 |
| Hypertension | 40 (72.7) | 36 (66.7) | 40 (74.1) | 0.773 |
| Diabetes mellitus | 13 (23.6) | 7 (13.0) | 9 (16.7) | 0.334 |
| Lesion characteristics | ||||
| Location | 0.102 | |||
| Proximal | 31 (56.4) | 21 (38.9) | 30 (55.6) | |
| Mid | 16 (29.1) | 22 (40.7) | 21 (38.9) | |
| Distal | 8 (14.6) | 11 (20.4) | 3 (5.6) | |
| Epicardial | 0.322 | |||
| LAD | 28 (50.9) | 32 (59.3) | 27 (50.0) | |
| LCX | 16 (29.1) | 13 (24.1) | 10 (18.5) | |
| RCA | 11 (20.0) | 9 (16.7) | 17 (31.5) | |
| Lesion length | 23.2±12.9 | 24.9±12.1 | 24.3±10.4 | 0.740 |
| Minimal lumen area | 3.7±2.1 | 2.7±1.4 | 2.5±1.4 | <0.001 |
| Minimal lumen diameter | 2.1±0.6 | 1.8±0.5 | 1.7±0.5 | <0.001 |
| Area stenosis | 56.1±1 8.3 | 59.3±16.5 | 67.1±17.6 | 0.004 |
| Diameter stenosis | 35.3±14.7 | 37.5±12.7 | 44.4±14.3 | 0.002 |
| %APV | 54.9±16.3 | 54.4±8.6 | 57.9±19.4 | 0.435 |
| Mean WSS | 89.2±36.1 | 188.9±31.0 | 408.7±132.7 | <0.001 |
| WSS range | 5.0–146.1 | 146.6–259.3 | 259.5–890.9 | |
APV indicates aggregate plaque volume; BSA, body surface area; LAD, left anterior descending; LCX, left circumflex; RCA, right coronary artery; WSS, wall shear stress.