Table 3.
Baseline Characteristics in 13 102 Patients Who Underwent AVR Between 1997 and 2013 According to Kidney Function
| All Patients n=13 102 | Normal Kidney Function n=9836 (75%) | Moderately Reduced Kidney Function n=3266 (25%) | |
|---|---|---|---|
| Age, yr, mean (SD) | 66.8 (12.9) | 64.3 (13.1) | 74.4 (8.5) |
| Female sex (%) | 5222 (39.9) | 3441 (35.0) | 1781 (54.5) |
| Civil status (%) | |||
| Not married | 5251 (40.1) | 3956 (40.2) | 1295 (39.7) |
| Education (%) | |||
| <10 years | 5222 (39.9) | 3783 (38.5) | 1439 (44.1) |
| 10 to 12 years | 5467 (41.7) | 4074 (41.4) | 1393 (42.7) |
| >12 years | 2413 (18.4) | 1979 (20.1) | 434 (13.3) |
| Region of birth (%) | |||
| Non‐Nordic countries | 769 (5.9) | 610 (6.2) | 159 (4.9) |
| Body mass index, kg/cm2, mean (SD) | 26.7 (4.5) | 26.7 (4.5) | 26.8 (4.7) |
| Biological valve prosthesis (%) | 8258 (63.0) | 5676 (57.7) | 2582 (79.1) |
| Diabetes mellitus (%) | 1713 (13.1) | 1164 (11.8) | 549 (16.8) |
| Atrial fibrillation (%) | 1850 (14.1) | 1151 (11.7) | 699 (21.4) |
| Hypertension (%) | 3210 (24.5) | 2142 (21.8) | 1068 (32.7) |
| Hyperlipidemia (%) | 1061 (8.1) | 782 (8.0) | 279 (8.5) |
| Stroke (%) | 1131 (8.6) | 769 (7.8) | 362 (11.1) |
| Peripheral vascular disease (%) | 1076 (8.2) | 805 (8.2) | 271 (8.3) |
| Chronic pulmonary disease (%) | 992 (7.6) | 705 (7.2) | 287 (8.8) |
| Past myocardial infarction (%) | 906 (6.9) | 569 (5.8) | 337 (10.3) |
| Past PCI (%) | 515 (3.9) | 350 (3.6) | 165 (5.1) |
| Past major bleeding event (%) | 620 (4.7) | 406 (4.1) | 214 (6.6) |
| Alcohol dependency (%) | 272 (2.1) | 223 (2.3) | 49 (1.5) |
| Liver disease (%) | 115 (0.9) | 83 (0.8) | 32 (1.0) |
| Cancer (%) | 930 (7.1) | 622 (6.3) | 308 (9.4) |
| eGFR, mL/min per 1.73 m2 (%) | |||
| >60 | 9836 (75.1) | 9836 (100.0) | — |
| 45 to 60 | 2377 (18.1) | — | 2377 (72.8) |
| 30 to 45 | 889 (6.8) | — | 889 (27.2) |
| Heart failure (%) | 2176 (16.6) | 1284 (13.1) | 892 (27.3) |
| Left ventricular ejection fraction (%) | |||
| >50 | 7564 (76.3) | 5979 (77.7) | 1585 (71.3) |
| 30 to 49 | 1905 (19.2) | 1425 (18.5) | 480 (21.6) |
| <30 | 449 (4.5) | 290 (3.8) | 159 (7.1) |
| Endocarditis (%) | 720 (5.5) | 565 (5.7) | 155 (4.7) |
| Emergent surgery (%) | 215 (1.6) | 162 (1.6) | 53 (1.6) |
| Isolated AVR (%) | 10 869 (83.0) | 7934 (80.7) | 2935 (89.9) |
| Year of surgery (%) | |||
| 1997 to 2001 | 2538 (19.4) | 1706 (17.3) | 832 (25.5) |
| 2002 to 2006 | 3816 (29.1) | 2717 (27.6) | 1099 (33.6) |
| 2007 to 2013 | 6748 (51.5) | 5413 (55.0) | 1335 (40.9) |
Normal kidney function (eGFR >60 mL/min per 1.73 m2) versus moderately reduced kidney function (eGFR 30–60 mL/min per 1.73 m2). Data are n (%), unless otherwise noted. AVR indicates aortic valve replacement; eGFR, estimated glomerular filtration rate; PCI, percutaneous coronary intervention.