Table 2.
Association Between Levels of IgM Anti‐MDA and Risk for MI and/or+Stroke (CVD), Among All Participants and Men and Women Separately
| Anti‐MDAa | All | Males | Females | |||
|---|---|---|---|---|---|---|
| Crude | Adjustedb | Crude | Adjusteda | Crude | Adjusteda | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| ≤10% | 2.16 (1.31–3.55) | 2.00 (1.19–3.36) | 2.62 (1.48–4.66) | 2.42 (1.32–4.42) | 1.14 (0.39–3.37) | 1.08 (0.36–3.29) |
| ≤25% | 1.76 (1.24–2.52) | 1.67 (1.16–2.41) | 1.98 (1.30–3.01) | 1.94 (1.25–3.01) | 1.32 (0.66–2.62) | 1.15 (0.57–2.31) |
| ≤33% | 1.48 (1.06–2.06) | 1.40 (0.99–1.97) | 1.79 (1.20–2.68) | 1.75 (1.15–2.68) | 0.94 (0.50–1.78) | 0.83 (0.43–1.62) |
| >50% | 0.82 (0.59–1.12) | 0.83 (0.59–1.16) | 0.71 (0.48–1.05) | 0.70 (0.46–1.06) | 1.10 (0.62–1.94) | 1.11 (0.61–2.01) |
| >66% | 0.68 (0.48–0.97) | 0.68 (0.48–0.98) | 0.54 (0.34–0.86) | 0.54 (0.33–0.86) | 0.99 (0.56–1.73) | 0.96 (0.54–1.73) |
| >75% | 0.84 (0.57–1.23) | 0.80 (0.53–1.19) | 0.59 (0.34–1.02) | 0.54 (0.31–0.96) | 1.29 (0.73–2.29) | 1.28 (0.70–2.36) |
| >90% | 0.85 (0.48–1.49) | 0.82 (0.46–1.46) | 0.34 (0.12–0.97) | 0.32 (0.11–0.98) | 1.62 (0.77–3.42) | 1.47 (0.68–3.19) |
Analyses are done by use of conditional logistic regression. CVD indicates cardiovascular disease; MDA, malondialdehyde; MI, myocardial infarction; OR, odds ratio.
a
For each percentile used as cut‐off, the remaining values formed the reference.
b
Adjustment for smoking, body mass index, type 2 diabetes mellitus, hypercholesterolemia, and hypertension.