Table 1. Description of fields in the Expanded Entry page.
| Field | Description | Source |
|---|---|---|
| Biological function | Protein/assembly function(s) with specification to the fuzzy region. | Uniprot, PubMed* |
| Domain organization/ sequence features | Topological organization of the protein, ID regions and domains. Main sequence features. Chimera sequences. | Pfam, Uniprot, PubMed |
| Structural evidence | Structural data demonstrating structural multiplicity or dynamic disorder in the complex. | PDB, BMRB, references |
| Biochemical evidence | Functional data demonstrating the impact of the fuzzy region in the formation, activity or regulation of the assembly. | references |
| Structure/mechanism | Molecular mechanism of how fuzzy region(s) modulate the conformational ensemble and the function of the assembly. | derived information, references |
| Mechanism category | Mechanistic classification of the fuzzy region. | derived information |
| Post-translational modification | The role of PTMs interfering with the fuzzy region and their impact on the activity of the complex. | Uniprot, references, derived information |
| Isoforms, context-dependence | Different isoforms, generated by alternative splicing affecting the fuzzy region. Functional and context-specific features of the different isoforms. | Uniprot, references, derived information |
| Medical relevance | Involvement in different diseases, specific roles of the fuzzy regions. | Uniprot, Cosmic, literature |
| Significance | The relationship between fuzziness and the function of the assembly. | derived information |
| Further reading | Additional references. | PubMed |
*PubMed means a general literature search, references refer to the articles specified in FuzDB.