Figure 1.
Computational workflow used to load RNA editing sites in REDIportal. Raw data in Fastq format are quality checked by FASTQC and aligned onto the reference human genome by STAR (14). REDItools (15) are then used to interrogate multiple read alignments using a large collection of known RNA editing sites from ATLAS repository (6) and RADAR database (11). WGS data are finally included in REDItools tables and, in turn, stored in REDIportal.
