Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 5;7:39732. doi: 10.1038/srep39732

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Binding mode of Compound-15 with the side chain of Thr68–a portion of the protein main-chain (light gray) is also shown. (B) A transient protein pocket modelled by combining binding modes of Compound-15 with NUPR1 main chain portions including residues 27–40 (orange) and 62–72 (green). (C) Numerous binding modes of Compound-8 with the protein main chain (N and C terminus in blue and red, respectively). (D) A transient protein pocket of Compound-9 with NUPR1 main chain portions including residues 8–11 (purple), 27–40 (orange) and 60–72 (green). PyMol⁵⁷ was used for all displays; hydrogens and protein main-chain oxygens are not shown, and protein backbone nitrogens are colored only for labelled residues.