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. 2017 Jan 5;120(1):99–109. doi: 10.1161/CIRCRESAHA.116.309937

Figure 4.

Figure 4.

Myeloid cell infiltration into the ischemic hindlimb 24 h post surgery. A and B, CD45+ and Gr1+ cells isolated from the gastrocnemius muscle of the ligated and nonligated hindlimbs from wild-type (WT) and AMPKα2ΔMC (ΔMC) mice 24 h after ligation (n=6 per group). C, In vitro stromal cell–derived factor-1–induced transendothelial migration of bone marrow–derived neutrophils from WT and AMPKα2ΔMC mice (n=4–6 per group). D, Ly6G+ and CRAMP+ neutrophils in ischemic semimembranosus muscles from WT and ΔMC mice 1 d post surgery. The images are representative of data obtained in an additional 3 animals per group. Upper: bar=200 µm; lower: bar=10 µm. *P<0.05, **P<0.01, ***P<0.001 vs WT. AMPK indicates AMP-activated protein kinase.