Effects of dietary walnuts on activation of JNK and p38 kinase in mice fed HFD for 6 weeks. (A) Equal amounts of whole liver lysates were used to determine the levels of P-JNK, JNK, P-p38K, or p38K by immunoblot analysis. The densitometric levels of (B) P-JNK and (C) P-p38K, determined by immunoblot analysis and normalized to JNK and p38K, respectively, are shown. All results are presented as mean ± SEM. Significance was determined by one-way ANOVA with the Tukey’s post hoc test (P<0.05) and is denoted by different letters.