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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Pediatr Infect Dis J. 2017 Jan;36(1):36–43. doi: 10.1097/INF.0000000000001342

Table 2.

Cost -Effectiveness of TB diagnostic algorithms in 1000 hypothetical children presenting to an urban Referral Hospital, Uganda

No. Patients with Active TB No. Diagnosed with True TB TB Deaths No. with true TB started on Treatment No. without TB started on TB treatment Total costa Incremental costb Total Effectiveness (YLG)c Incremental Effectivness Incremental Cost-effectiveness (ICER) - USD/YLG
Clinical Diagnosis 140 96 29 90 147 66769 0 22480 0 0
Clinical Diagnosis plus MODS 140 117 26 108 163 95365 28596 22750 270 106
Clinical Practice plus Xpert 140 115 24 110 163 105691 38922 22790 310 126
Treat All children presenting with suspected TB 140 140 18 140 860 193662 126893 23170 690 184
a

Total cost: includes cost of diagnosis, treatment of true and false positives.

b

Incremental cost (and effectiveness): cost-effectiveness is relative to current clinical practice alone scenario (for example: $95,364.59-$66,769.04=an incremental cost of $28,595.55).

c

Total effectiveness reflects the underlying life expectancy of 54 years for 1000 kids applying a discount of 3%.