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. 2016 Dec;57(15):6911–6918. doi: 10.1167/iovs.16-21201

Figure 7.

Figure 7

Regression of drusen in a patient receiving high-dose oral atorvastatin. (A) An otherwise healthy patient with age-related macular degeneration (AMD) with bilateral, large, soft, confluent macular drusenoid pigment epithelial detachments and pigmentary alterations on color fundus photography (upper figure parts), and decreasing visual acuity with significant distortion. (B) Spectral-domain optical coherence tomography (SD-OCT) showing the significant extent of these deposits and the overlying retinal pigment epithelium (RPE) and photoreceptor architectural distortion (upper figure parts). The patient was started on atorvastatin 10 mg and escalated to 80 mg over 9 months. Six months after 80 mg atorvastatin, visual acuity improved by 12 letters to 20/20. Fundus photographs and SD-OCT revealed complete disappearance of the drusen without accompanying atrophy of the retinal pigment epithelium (lower figure parts). Reprinted with permission from Vavvas DG, Daniels AB, Kapsala ZG, et al. Regression of some high-risk features of age-related macular degeneration (AMD) in patients receiving intensive statin treatment. EBioMedicine. 2016;5:198–203. Copyright 2016 by Vavvas DG, Daniels AB, Kapsala ZG, et al.