Table 2.

(Photo)cytotoxicity of [d‐2][PF₆]₂ and [l‐2][PF₆]₂ expressed as effective concentrations (EC₅₀) in the dark and after irradiation with blue light, and photocytotoxicity index (PI) values versus A549 and MCF‐7 cells. +95% and −95 % confidence intervals are also indicated (in μm).

	A549					MCF‐7
Complex	EC50 dark[a]		EC50 454 nm[b]		PI[c]	EC50 dark[a]		EC50 454 nm[b]		PI[c]
[d‐2](PF6)2	19	+4.0	0.72	+0.16	26	9.6	+2.9	0.86	+0.21	11
		−3.3		−0.13			−2.3		−0.17
[l‐2](PF6)2	50	+17	0.58	+0.13	86	18	+3.8	0.61	+0.28	30
		−13		−0.11			−3.1		−0.19

[a] Cells were incubated with the Ru complex for 24 h. [b] Cells were incubated with the Ru complex for 24 h, and the media was refreshed before irradiation with blue light (5 min at λ _exc=450 nm with (3.2±0.2) J cm⁻²). [c] PI=EC_50(dark)/EC_50(450nm).