TABLE 1.
Baseline (weeks 13–17) | Salt-challenged (weeks 18–21) | |||||
Congenic strains (no. of rats) | Systolic BP | Diastolic BP | Pulse pressure | Systolic BP | Diastolic BP | Pulse pressure |
SHRSP (n = 26) | – | – | – | – | – | – |
WKY (n = 13) | F = 152.96, P < 0.001 | F = 90.99, P < 0.001 | F = 96.85, P < 0.001 | F = 195.41, P < 0.001 | F = 133.53, P < 0.001 | F = 70.59, P < 0.001 |
SP.WKYGla3a (n = 10) | F = 17.14, P < 0.001 | F = 10.99, P = 0.002 | F = 9.01, P = 0.005 | F = 44.84, P < 0.001 | F = 39.14, P < 0.001 | F = 6.781, P = 0.014 |
SP.WKYGla3b (n = 6) | F = 1.77, P = 0.193 | F = 2.92, P = 0.97 | F = 0.08, P = 0.778 | F = 5.88, P = 0.022 | F = 9.32, P = 0.005 | F = 1.40, P = 0.245 |
SP.WKYGla3c (n = 5) | F = 7.20, P = 0.012 | F = 5.31, P = 0.028 | F = 2.70, P = 0.111 | F = 25.32, P < 0.001 | F = 18.45, P < 0.001 | F = 9.40, P = 0.005 |
SP.WKYGla3d (n = 7) | F = 23.64, P < 0.001 | F = 16.24, P < 0.001 | F = 11.97, P = 0.002 | F = 39.20, P < 0.001 | F = 31.67, P < 0.001 | F = 10.90, P = 0.002 |
SP.WKYGla3e (n = 9) | F = 28.47, P < 0.001 | F = 11.83, P = 0.002 | F = 6.63, P = 0.015 | F = 55.73, P < 0.001 | F = 35.16, P < 0.001 | F = 8.36, P = 0.007 |
SP.WKYGla3f (n = 6) | F = 1.09, P = 0.305 | F = 0.92, P = 0.344 | F = 0.31, P = 0.583 | F = 4.79, P = 0.037 | F = 5.09, P = 0.032 | F = 0.01, P = 0.916 |
SP.WKYGla3g (n = 7) | F = 0.04, P = 0.843 | F = 0.35, P = 0.561 | F = 0.54, P = 0.468 | F = 0.70, P = 0.409 | F = 1.61, P = 0.213 | F = 1.37, P = 0.251 |
BP, blood pressure; SHRSP, stroke-prone spontaneously hypertensive; WKY, Wistar–Kyoto.