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. 2017 Jan 4;35(2):319–329. doi: 10.1097/HJH.0000000000001155

TABLE 4.

WKYGla versus SHRSPGla NGS sequence variants on RNO3 within the region in-common between congenic strains 3d and 3f

SNP consequences INDEL consequences
INTERGENIC 1930 INTERGENIC 406
UPSTREAM 808 UPSTREAM 171
DOWNSTREAM 711 DOWNSTREAM 134
3PRIME_UTR 74 3PRIME_UTR 4
5PRIME_UTR 15 5PRIME_UTR 0
INTRONIC 3946 INTRONIC 805
SYNONYMOUS_CODING 77 SYNONYMOUS_CODING 0
NON_SYNONYMOUS_CODING 33 NON_SYNONYMOUS_CODING 2
STOP_GAINED 0 FRAMESHIFT_CODING 1
STOP_LOST 0 COMPLEX_INDEL 0
ESSENTIAL_SPLICE_SITE 2 ESSENTIAL_SPLICE_SITE 0
SPLICE_SITE 13 SPLICE_SITE 1
WITHIN_MATURE_miRNA 0 WITHIN_MATURE_miRNA 0
WITHIN_NON_CODING_GENE 8 WITHIN_NON_CODING_GENE 0

NGS, next-generation sequencing; RNO3, rat chromosome 3; SHRSP, stroke-prone spontaneously hypertensive; SNP, single-nucleotide polymorphism; WKY, Wistar–Kyoto.