Figure 2. STZ-induced diabetes increases CML levels in blood and muscle tissue.
Blood and muscle tissue was collected from the mice at the end of the study. An ELISA was used to assess CML levels in the blood serum (A) and muscle lysates (B). CML was increased in the diabetic groups of each genotype with no differences in overall levels between the genotypes. Mean and SEM are plotted and * indicates p<0.05 and ** indicates p<0.01 (n=8 for blood serum and n=6 for tissue lysate).