Figure 2.

Remosome model placed within the RSC remodeller. Two views of a nucleosome containing a 42 bp insertions at the dyad (DNA shown in cyan, histone core in gray) manually docked inside the 3D reconstruction of the RSC complex calculated from cryo-EM data.³ (shown in yellow). A representative snapshot of the remosome model was taken from a 0.5 μs MD simulation¹⁷ converted to a 25 Å-resolution density map to match the RSC data. DNA in the looped nucleosome is shown up to 25 bp from the ends, to account for the possible rearrangements in these zones.³ Molecular graphics were generated with the UCSF Chimera package.^27,28