Table 5.
Adjusted odds ratios for participating in various levels of genetic research, India Sample
| Participate | Secondary analysis | Share with private company | Cell lines | |
|---|---|---|---|---|
| Yes v No | Yes v No | Yes v No | Yes v No | |
| n=192 v n=116 | n=171 v. n=172 | n=129 v n=205 | n=161 v n=160 | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Gender | ||||
| Female | -- | 0.6 (0.4, 1.0) | -- | -- |
| Male | -- | Reference | -- | -- |
| What best describes your education? | ||||
| High school or less | 4.2 (1.4, 12.7) | 2.5 (1.0, 6.2) | -- | 3.5 (1.3, 9.7) |
| Undergraduate | Reference | Reference | -- | Reference |
| Graduate | 2.7 (1.5, 4.9) | 1.3 (0.8, 2.1) | -- | 1.7 (1.0, 2.9) |
| Owns a car | ||||
| No | -- | 0.6 (0.4, 1.0) | -- | -- |
| Yes | -- | Reference | -- | -- |
| Muslim | ||||
| No | -- | -- | -- | 2.5 (1.1, 5.6) |
| Yes | -- | -- | -- | Reference |
| Ethics Position Categories (continuous)a | ||||
| Situationalists | 0.6 (0.3, 1.2) | -- | -- | -- |
| Absolutists | 1.2 (0.5, 2.5) | -- | -- | -- |
| Subjectivists | 0.5 (0.2, 1.1) | -- | -- | -- |
| Exceptionists | Reference | -- | -- | -- |
| Multidimensional Health Locus of Control Scales (continuous)b | ||||
| Internal score | -- | -- | -- | -- |
| Powerful other score | 1.0 (1.0, 1.1) | 1.0 (1.0, 1.1) | 1.1 (1.1, 1.2) | 1.1 (1.0, 1.1) |
| Chance score | 1.1 (1.0, 1.1) | 1.1 (1.0, 1.1) | 1.1 (1.0, 1.1) | -- |
| Doctors score | -- | -- | -- | 1.2 (1.1, 1.3) |
| Other people score | -- | -- | -- | -- |
| Genetic research could help find new treatments | ||||
| Very likely or likely | 2.3 (1.0, 5.4) | -- | -- | 2.3 (1.0, 5.4) |
| Neutral, unlikely, or very unlikely | Reference | -- | -- | Reference |
| It may help my children or future families | ||||
| Very likely or likely | 2.6 (1.2, 5.5) | 2.8 (1.6, 4.9) | 2.8 (1.5, 5.3) | 1.9 (0.9, 4.2) |
| Neutral, unlikely, or very unlikely | Reference | Reference | Reference | Reference |
| It would help us understand inherited diseases | ||||
| Very likely or likely | 2.1 (1.0, 4.8) | -- | -- | 1.8 (0.8, 4.0) |
| Neutral, unlikely, or very unlikely | Reference | -- | -- | Reference |
| I have concerns | ||||
| No | -- | 1.7 (1.0, 2.6) | 1.9 (1.2, 3.2) | 1.4 (0.8, 2.3) |
| Yes | -- | Reference | Reference | Reference |
| I am concerned about privacy and confidentiality of data | ||||
| No | -- | -- | 1.6 (0.8, 3.1) | -- |
| Yes | -- | -- | Reference | -- |
| I am concerned about my family's history not being protected | ||||
| No | 1.5 (0.9, 2.6) | -- | -- | 1.9 (1.1, 3.2) |
| Yes | Reference | -- | -- | Reference |
| I am concerned about how and where the data will be kept. | ||||
| No | -- | -- | 1.6 (1.1, 1.2) | -- |
| Yes | -- | -- | Reference | -- |
Variables not included in any of the final models include: age, own a house, and general health questions.
a
Ethical positioning categories: Situationalists favor securing the best possible consequence for all concerned; Absolutists believe people should act in ways that are consistent with moral rules; Subjectivists base their choices on personal considerations; and Exceptionalists endorse moral rules as guides for action but admit that following rules will not always lead to the best outcome for all
b
MHLC scales for internal, chance, and powerful others have a possible range of 6-36; doctors and others scale has a possible range of 3-18.