Table 6.
Adjusted odds ratios for participating in various levels of genetic research, US Sample
| Participate | Secondary analysis | Share with private company | Cell lines | |
|---|---|---|---|---|
| Yes v No | Yes v No | Yes v No | Yes v No | |
| n=228 v n=174 | n=153 v n=294 | n=114 v n=305 | n=152 v. n=231 | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Not Christian | ||||
| No | -- | -- | -- | 1.6 (1.0, 2.6) |
| Yes | -- | -- | -- | Reference |
| Ethical positioning score (continuous)a | ||||
| Ethics - Idealism | -- | -- | -- | -- |
| Ethics - Relativism | -- | -- | -- | 1.1 (1.0, 1.1) |
| Multidimensional Health Locus of Control Scales (continuous)b | ||||
| Internal score | 1.0 (1.0, 1.1) | -- | -- | -- |
| Powerful other score | -- | -- | -- | -- |
| Chance score | -- | -- | 1.0 (1.0, 1.1) | 1.0 (1.0, 1.1) |
| Doctors score | 1.1 (1.0, 1.2) | -- | -- | -- |
| Other people score | -- | -- | -- | -- |
| Genetic research could help find new treatments | ||||
| Very likely or likely | 4.7 (2.0, 11.2) | 3.1 (1.3, 7.2) | -- | 5.5 (1.9, 16.0) |
| Neutral, unlikely, or very unlikely | Reference | Reference | -- | Reference |
| It may help my children or future families | ||||
| Very likely or likely | 3.0 (1.2, 7.1) | 3.6 (1.5, 8.6) | 10.9 (3.2, 36.7) | 8.3 (2.6, 27.0) |
| Neutral, unlikely, or very unlikely | Reference | Reference | Reference | Reference |
| It would help us understand inherited diseases | ||||
| Very likely or likely | 3.7 (1.3, 10.8) | -- | -- | -- |
| Neutral, unlikely, or very unlikely | Reference | -- | -- | -- |
| I have concerns | ||||
| No | 1.9 (1.0, 3.5) | 2.7 (1.6, 4.6) | 2.1 (1.2, 3.7) | 2.0 (1.0, 3.7) |
| Yes | Reference | Reference | Reference | Reference |
| Not concerned about my family's history not being protected | ||||
| Yes | 3.6 (2.1, 6.0) | 1.8 (1.1, 3.2) | 2.2 (1.2, 4.1) | 2.7 (1.5, 4.9) |
| No | Reference | Reference | Reference | Reference |
| Not concerned about how and where the data will be kept. | ||||
| Yes | -- | 1.8 (1.0, 3.5) | 2.3 (1.2, 4.6) | 1.8 (0.9, 3.8) |
| No | -- | Reference | Reference | Reference |
Variables not included in any of the final models include: age, gender, education, own a car, own a house, and general health questions.
a
Ethical positioning questions are divided into two scores: 1) Relativism (possible scores from 6-30) and 2) Idealism (possible score of 5-25). The relativism score pertains to an individual's moral principles. The idealism score measures an individual's concern for consequences.
b
MHLC scales for internal, chance, and powerful others have a possible range of 6-36; doctors and others scale has a possible range of 3-18.