Table 2.
Phyla showing significant differences among the cohort groups using DESeq2. Stated p-values were adjusted for multiple hypothesis testing using the method of Benjamini-Hochberg (22).
| Cohort Groups | Phylum Name | log2FoldChange | Adjusted p-values |
|---|---|---|---|
| Controls Compared to fCDI | |||
| Higher in Controls | Actinobacteria | −2.408 | 0.0004 |
| Higher in Controls | Verrucomicrobia | −1.533 | 0.0042 |
| Higher in fCDI | Fusobacteria | 1.644 | 0.0342 |
| Higher in fCDI | Synergistetes | 2.195 | 0.0004 |
| Higher in fCDI | TM7 | 1.186 | 0.0381 |
| Controls Compared to rCDI | |||
| Higher in Controls | Euryarchaeota | −2.000 | 0.0076 |
| Higher in Controls | Verrucomicrobia | −1.031 | 0.063 |
| Higher in Controls | Actinobacteria | −2.624 | 0.0001 |
| Higher in Controls | Bacteroidetes | −2.381 | 0.0004 |
| Higher in rCDI | TM7 | 1.466 | 0.011 |
| Higher in rCDI | Fusobacteria | 7.300 | 0 |
| Higher in rCDI | Proteobacteria | 3.870 | 0 |
| rCDI compared fCDI | |||
| Higher in fCDI | Bacteroidetes | −2.249 | 0.0008 |
| Higher in fCDI | Euryarchaeota | −2.848 | 0.0001 |
| Higher in fCDI | Synergistetes | −2.293 | 0.0005 |
| Higher in rCDI | Proteobacteria | 2.986 | 0 |
| Higher in rCDI | Fusobacteria | 5.656 | 0 |