Fig. 7.
Morris water maze test 4 months after 4 h isoflurane (iso) anesthesia (n = 13) or sham anesthesia (control, n = 11) in 16-month-old rats. During the cued trials (data not shown), the submerged platform was marked with a flag, which was removed during the place trials (A), in which spatial memory is tested by measuring time-integrated distance to the platform allowing some credit to be assigned for searching in the general vicinity of the platform. The 90-s probe trial (platform removed) tests memory retention (B). The dotted line indicates the likelihood of time spent in quadrants by chance. No difference was found between groups in any of the measured parameters. CW = clockwise.