Figure 4.

Component- and pattern-motion selectivity population results. A–D, Scatter plot of component and pattern partial correlation coefficients calculated for each directionally selective L2/3 pyramidal neuron recorded in mouse V1 (A, B), and previous studies in cat/primate V1 (C), and higher visual areas (D), following the study by Smith et al. (2005). The x-axis plots the R_c value for each cell (see Materials and Methods). The y-axis plots the R_p value. Black line boundaries demarcate statistical significance levels calculated from the Fisher transform (see Materials and Methods; Smith et al., 2005): solid black line, p = 0.95; broken black line, p = 0.9. The p = 0.9 value has generally been used by previous investigators (Movshon and Newsome, 1996; Smith et al., 2005). A, Results for the 60° CA plaid. Red dots denote the positions of neurons 1 and 2 (CM-selective responses), and 5 and 6 (PM-selective responses) from Figure 3. Black dots, Data obtained using square-wave gratings and plaids (six animals). B, Results for the 120° CA plaid. Blue dots, Neurons 3 and 4 (CM-selective responses), and neurons 7 and 8 (PM-selective responses) from Figure 3; black dots, data obtained using square-wave gratings and plaids (six animals); gray dots, data obtained using sine-wave gratings and plaids (two animals). C, Literature results from cat and monkey V1 under anesthesia. Data were digitized from the studies by Gizzi et al. (1990), Movshon and Newsome (1996), and Guo et al. (2004). Black filled circles, Monkey V1 (Movshon and Newsome, 1996); stars, cat V1 (Gizzi et al., 1990); triangles, monkey V1, layers 4 and 6 (Guo et al., 2004). Unlike mouse V1 and extrastriate areas of cats and primates, primate and cat V1 under anesthesia contains a large majority of CM-selective neurons with only a small minority of unclassified cells and virtually no PM-selective cells. D, Aggregate population plot of direction-selective cells from cat and monkey extrastriate visual cortical areas and higher-order thalamic nuclei derived from the literature. Data were digitized from the studies by Movshon et al. (1985), Scannell et al. (1996), and Merabet et al. (1998). Open circles, Monkey V5/MT (Movshon et al., 1985); crosses, cat anterior ectosylvian visual area (AEV; Scannell et al., 1996); and rhomboids, cat lateral posterior nucleus of thalamus (LP)–pulvinar complex (Merabet et al., 1998). Note that the shape of the distribution we observe in A and B from mouse V1 is similar to the distributions observed in the extrastriate areas of cats and primates.