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. 2017 Jan 5;7:40159. doi: 10.1038/srep40159

Figure 1. NENS or Nic uncouples mitochondrial respiration but has no effect on body weight, energy intake or body composition.

Figure 1

(a) Oxygen consumption of isolated C57BL/6 hepatocytes using the Clark electrode with oligomycin and either NENS or Nic, (b) weekly body weight, (c) weekly food intake and (d) total fat % measurements using EcoMRI, as indicated in the time points. n = 12 per group. Statistical significance (P) was determined by multiple comparisons and repeated measures Two-way ANOVA test. The data is showed as the mean ± S.E.M. *p < 0.05 or ***p < 0.001 compared to the control chow or control high fat mice.