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. 2017 Jan 5;27:16084. doi: 10.1038/npjpcrm.2016.84

Table 2. Characteristics of the 700 patients with a new diagnosis of COPD divided into participants with possible ACOS and COPD only.

  Any ACOS (n=264) COPD only (n=436) P-value
Age (years) 61.9 (10.9) 63.6 (10.2) P=0.04
BMI 26.2 (5.7) 25.5 (4.6) NS
Pack-years 39.9 (22.8) 39.5 (23.4) NS
FEV1 (l) 1.75 (0.67) 1.99 (0.68) P<0.001
FEV1 (%pred.) 66.6 (18.7) 73.8 (18.8) P<0.001
FEV1/FVC 0.60 (0.08) 0.62 (0.07) P<0.001
MRC score 2.2 (0.8) 1.8 (0.8) P<0.001
BD reversibility (l) 0.18 l (0.22) 0.03 (0.14) P<0.001

Abbreviations: ACOS, asthma–COPD overlap syndrome; BD, bronchodilator; BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1/FVC, forced expiratory volume 1/forced vital capacity; MCR, Medical Research Council.