Table 2. Characteristics of the 700 patients with a new diagnosis of COPD divided into participants with possible ACOS and COPD only.
Any ACOS (n=264) | COPD only (n=436) | P-value | |
---|---|---|---|
Age (years) | 61.9 (10.9) | 63.6 (10.2) | P=0.04 |
BMI | 26.2 (5.7) | 25.5 (4.6) | NS |
Pack-years | 39.9 (22.8) | 39.5 (23.4) | NS |
FEV1 (l) | 1.75 (0.67) | 1.99 (0.68) | P<0.001 |
FEV1 (%pred.) | 66.6 (18.7) | 73.8 (18.8) | P<0.001 |
FEV1/FVC | 0.60 (0.08) | 0.62 (0.07) | P<0.001 |
MRC score | 2.2 (0.8) | 1.8 (0.8) | P<0.001 |
BD reversibility (l) | 0.18 l (0.22) | 0.03 (0.14) | P<0.001 |
Abbreviations: ACOS, asthma–COPD overlap syndrome; BD, bronchodilator; BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1/FVC, forced expiratory volume 1/forced vital capacity; MCR, Medical Research Council.