Table 3. Characteristics of the 264 patients with possible ACOS, divided according to the presence of self-reported wheeze (ACOS wheeze) and/or a positive bronchodilator reversibility test (ACOS BD reversibility).
| ACOS wheeze and ACOS BD reversibility (n=39) | ACOS wheeze (n=151) | ACOS BD reversibility (n=74) | |
|---|---|---|---|
| Age (years) | 60.4 (12.0) | 61.5 (10.9) | 62.2 (11.2) |
| BMI | 25.3 (5.6) | 26.8 (5.9) | 25.0 (5.1) |
| Pack-years | 38.4 (18.3) | 40.4 (22.6) | 38.5 (21.9) |
| FEV1 (l) | 1.71 (0.70) | 1.79 (0.67) | 1.64 (0.68) |
| FEV1 (%pred.) | 66.4 (16.4) | 65.7 (18.7) | 68.0 (17.9) |
| FEV1/FVC | 0.57 (0.08) | 0.60 (0.08) | 0.59 (0.08) |
| MRC score | 2.5 (1.1)a | 2.3 (0.9)a | 2.1 (0.9)a |
Abbreviations: ACOS, asthma–COPD overlap syndrome; BD, bronchodilator; BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1/FVC, forced expiratory volume 1/forced vital capacity; MCR, Medical Research Council.
a
P<0.01 for ACOS wheeze and BD reversibility compared with ACOS wheeze and ACOS BD reversibility.