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. 2017 Jan 5;7:528. doi: 10.3389/fphar.2016.00528

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Copyright © 2017 Wei, Yi, Gu, Hou, Lu, Yu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Up-regulation of KCa3.1 channels in astrocytes and neurons in Tg^APP/PS1 mouse brains. Immunofluorescence double staining of KCa3.1 (green) with GFAP, NeuN, or Iba1 (red) in brain sections of 9 month old wild type (WT) and Tg^APP/PS1 mice. Co-staining of (A) KCa3.1 and GFAP, (B) KCa3.1 and NeuN, and (C) KCa3.1 and Iba1 in WT and Tg^APP/PS1 mice. Arrows indicate co-labeling of (A) KCa3.1 and GFAP, (B) KCa3.1 and NeuN, and (C) KCa3.1 and Iba1. Views are enlarged in the adjacent panels. Nuclei are stained blue with DAPI. Scale bars: (A) 25 μm, (B) 50 μm, and (C) 25 μm.