Insulin independence rate |
25%–50% at 5 years in international cohort studies (~50% in some experienced centers [7,12]) |
70% at 5 years |
Graft survival (fasting C-peptide > 0.3 ng/mL, free of severe hypoglycemia) |
~70% at 5 years (75% at 5 years in the French-Swiss GRAGIL group [14]) |
~70% at 5 years |
Success rate according to the clinical setting |
Islet alone = islet after kidney = simultaneous islet and kidney |
Simultaneous pancreas and kidney > pancreas alone = pancreas after kidney |
Morbidity/mortality |
Very low procedure complication rate, low mortality |
Perioperative morbidity, complications of exocrine pancreas, and late surgical complications |