Table 1.

Clinical, Demographic, and Microbiologic Features Are Significantly Associated with Airway Bacterial β-Diversity in Patients with HIV and Pneumonia

Variable	Sample (n)	Yes/No*	Min–Max (Median)	PERMANOVA
				R2	P Value
Clinical and demographic
70-day mortality†	182	143/39 (live/dead)		0.006	0.053
Alcohol ever consumed	182	113/69		0.015	0.045
Ceftriaxone at bronchoscopy	174	54/120		0.061	0.001
Ceftriaxone within last 2 wk	178	137/41		0.016	0.040
Culture identified Aspergillus	157	15/142		0.038	0.004
Sex	182	110/72 (F/M)		0.021	0.017
TB-positive by culture	182	40/1/141 (positive/scanty/negative)		0.027	0.021
Microbiologic
Chao1	182		170–1,326 (484.1)	0.080	0.001
Faith’s phylogenetic diversity	182		8.792–45.83 (21.97)	0.091	0.001
Observed species	182		39–865 (340.5)	0.076	0.001
Shannon diversity	182		0.642–6.427 (4.011)	0.169	0.001
Simpson diversity	182		0.112–0.977 (0.867)	0.154	0.001

Definition of abbreviations: Max = maximum;  Min = minimum; PERMANOVA = permutational multivariate analysis of variance; TB = tuberculosis.

^*Unless otherwise noted.

^†PERMANOVA value calculated using a Canberra distance matrix.