Table 2.

MEM effect on MCCB performance

MCCB cognitive domain T-score	All subjects
Main analysis with diagnosis, dose, and test order as between-subject factor
Diagnosis (Dx)	F = 56.17, df (1,72), p < 0.0001
Drug	F = 12.26, df (1,72), p = 0.0008
Domain	F = 16.23, df (6, 432), p < 0.0001
Dose	F < 1
Test order	F < 1
Dose × test order	F = 4.09, df (1,72), p < 0.05
Drug × dose	F = 8.73, df (1,72), p = 0.004
Drug × test order	F = 85.74, df (1,72), p < 0.0001
Domain × Dx	F = 4.57, df (6, 432), p = 0.0002
Drug × dose × test order	F = 5.45, df (1,72), p < 0.05
Drug × domain × dose	F = 3.06, df (6, 432), p = 0.006
Drug × domain × test order	F = 16.39, df (6, 432), p < 0.0001
Drug × domain × test order × Dx	F = 2.09, df (6, 432), p = 0.05
MCCB composite T-score	All subjects
Main analysis with diagnosis, dose, and test order as between-subject factors
Dx	F = 55.71, df (1,72), p < 0.0001
Drug	F < 1
Drug × test order	F = 39.58, df (1,72), p < 0.0001
Drug × dose	F = 4.15, df (1,72), p < 0.05
OCME cognitive domain T-score	All subjects
Main analysis with diagnosis and dose as between-subject factor
Diagnosis	F < 1
Dose	F = 7.84, df (1,76), p = 0.006
Domain × dose	F = 2.51, df (6, 456), p = 0.02