Table 2.
Prevalence of diseases and prescribed drugs
| Total population | ≤69 years | 70–79 years | ≥80 years | |||||
|---|---|---|---|---|---|---|---|---|
| No hip fracture | Hip fracture | No hip fracture | Hip fracture | No hip fracture | Hip fracture | No hip fracture | Hip fracture | |
| No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | |
| ICD-10 diagnosis chapter | ||||||||
| Certain infectious and parasitic diseases (A–B) | 8052 (6.9) | 87 (18.2) | 3798 (4.7) | 9 (14.1) | 1764 (8.2) | 12 (10.4) | 2490 (16.8) | 66 (22.1) |
| Malignant neoplasms (C) | 8452 (7.2) | 66 (13.8) | 3845 (4.8) | 11 (17.2) | 2451 (11.4) | 19 (16.5) | 2156 (14.6) | 36 (12.1) |
| Non-malignant neoplasms (D00-D48) | 5674 (4.8) | 43 (9.0) | 3481 (4.3) | 7 (10.9) | 1129 (5.3) | 11 (9.6) | 1064 (7.2) | 25 (8.4) |
| Diseases of the blood/blood-forming organs (D50–89) | 4265 (3.6) | 80 (16.8) | 1631 (2.0) | 10 (15.6) | 896 (4.2) | 15 (13.0) | 1738 (11.8) | 55 (18.5) |
| Endocrine, nutritional and metabolic disorders (E) | 14,602 (12.5) | 148 (31.0) | 6839 (8.5) | 16 (25.0) | 3886 (18.1) | 39 (33.9) | 3877 (26.2) | 93 (31.2) |
| Mental and behavioral disorders (F) | 7971 (6.8) | 118 (24.7) | 4812 (6.0) | 15 (23.4) | 1283 (6.0) | 26 (22.6) | 1876 (12.7) | 77 (25.8) |
| Diseases of the nervous system (G) | 7250 (6.2) | 90 (18.9) | 3532 (4.4) | 13 (20.3) | 1767 (8.2) | 21 (18.3) | 1951 (13.2) | 56 (18.8) |
| Diseases of the eye and adnexa (H00-H59) | 3883 (3.3) | 52 (10.9) | 1523 (1.9) | 3 (4.7) | 944 (4.4) | 11 (9.6) | 1416 (9.6) | 38 (12.8) |
| Diseases of the ear and mastoid process (H60-H95) | 2754 (2.4) | 23 (4.8) | 1441 (1.8) | 2 (3.1) | 611 (2.8) | 5 (4.3) | 702 (4.7) | 16 (5.4) |
| Diseases of the circulatory system (I) | 29,018 (24.8) | 283 (59.3) | 12,690 (15.7) | 20 (31.3) | 7730 (36.0) | 66 (57.4) | 8598 (58.1) | 197 (66.1) |
| Diseases of the respiratory system (J) | 10,682 (9.1) | 117 (24.5) | 5198 (6.4) | 14 (21.9) | 2485 (11.6) | 19 (16.5) | 2999 (20.3) | 84 (28.2) |
| Diseases of the digestive system (K) | 18,450 (15.8) | 144 (30.2) | 10,726 (13.3) | 12 (18.8) | 3860 (18.0) | 31 (27.0) | 3864 (26.1) | 101 (33.9) |
| Diseases of the skin and subcutaneous tissue (L) | 3543 (3.0) | 23 (4.8) | 1977 (2.4) | 3 (4.7) | 727 (3.4) | 8 (7.0) | 839 (5.7) | 12 (4.0) |
| Diseases of the musculoskeletal system and connective tissue (M) | 17,953 (15.3) | 151 (31.7) | 9181 (11.4) | 12 (18.8) | 4234 (19.7) | 32 (27.8) | 4538 (30.7) | 107 (35.9) |
| Diseases of the genitourinary system (N) | 15,853 (13.5) | 154 (32.3) | 8037 (10.0) | 12 (18.8) | 3415 (15.9) | 32 (27.8) | 4401 (29.8) | 110 (36.9) |
| Injury, poisoning and certain other consequences of external causes (S–T) | 19,399 (16.6) | 203 (42.6) | 10,559 (13.1) | 25 (39.1) | 4010 (18.6) | 42 (36.5) | 4830 (32.7) | 136 (45.6) |
| Fracture of the neck, thorax, spine, arm, hip, leg, ankle (S12/S22/S32/42/52/62/72/82) | 9722 (8.3) | 148 (31.0) | 4576 (5.7) | 20 (31.3) | 2007 (9.3) | 30 (26.1) | 3139 (21.2) | 98 (32.9) |
| Drug (ATC code) | ||||||||
| Drugs used in diabetes (A10) | 10,686 (9.1) | 57 (11.9) | 5714 (7.1) | 6 (9.4) | 2964 (13.8) | 21 (18.3) | 2008 (13.6) | 30 (10.1) |
| Corticosteroids systemic (H02) | 7984 (6.8) | 41 (8.6) | 4542 (5.6) | 8 (12.5) | 1922 (8.9) | 13 (11.3) | 1520 (10.3) | 20 (6.7) |
| Antiparkinson drugs (N04) | 2027 (1.7) | 26 (5.5) | 879 (1.1) | 4 (6.3) | 563 (2.6) | 11 (9.6) | 585 (4.0) | 11 (3.7) |
| Benzodiazepines (N05BA) | 9018 (7.7) | 103 (21.6) | 4178 (5.2) | 7 (10.9) | 2004 (9.3) | 19 (16.5) | 2836 (19.2) | 77 (25.8) |
| Opioid, anxiolytic, hypnotics and sedatives drugsa | 33,119 (28.3) | 267 (56.0) | 18,048 (22.4) | 25 (39.1) | 7115 (33.1) | 61 (53.0) | 7956 (53.8) | 181 (60.7) |
| Antidepressant drugs (N06A) | 16,006 (13.7) | 162 (34.0) | 9332 (11.6) | 14 (21.9) | 2909 (13.5) | 35 (30.4) | 3765 (25.5) | 113 (37.9) |
| Cardiovascular system drugs (C) | 59,165 (50.6) | 362 (75.9) | 31,529 (39.1) | 35 (54.7) | 14,670 (68.2) | 87 (75.7) | 12,966 (87.7) | 240 (80.5) |
| Nervous system drugs (N) | 48,342 (41.3) | 356 (74.6) | 27,216 (33.7) | 38 (59.4) | 10,207 (47.5) | 80 (69.6) | 10,919 (73.8) | 238 (79.9) |
| Fall-risk-increasing drugsb | 23,990 (20.5) | 250 (52.4) | 10,338 (12.8) | 19 (29.7) | 6081 (28.3) | 55 (47.8) | 7571 (51.2) | 176 (59.1) |
| Five or more dispensed drugs during 1 yearc | 57,005 (48.7) | 394 (82.6) | 29,877 (37.0) | 44 (68.8) | 13,933 (64.8) | 90 (78.3) | 13,195 (89.2) | 260 (87.2) |
| Ten or more dispensed drugs during 1 yearc | 25,030 (21.4) | 249 (52.2) | 10,698 (13.3) | 25 (39.1) | 6684 (31.1) | 56 (48.7) | 7648 (51.7) | 168 (56.4) |
Prevalence of diseases in the in-patient register between 1987 and 2010 for the total population (approximated by all in-patient care registered in Uppsala County for patients alive January 1, 2010) and between 1987 and day before date of fracture for subjects with hip fracture. Prevalence of prescribed drugs from the prescribed drug register in 2010 for the total population (approximated by all prescribed drugs registered in Uppsala County for patients alive January 1, 2010) and for 1 year before date of fracture for subjects with hip fracture
aOne or more of N02A, N05B-C
bOne or more of N02A, N03A, N04A-B, N05A-C, N06A AND one or more of C01A, C01BA, C01D, C02, C03, C07-C09, G04CA
cAny ATC code