Table 1.
Correctional (r) matrix for gene expression and key behavioral phenotypes
|
csnkle
|
grid2
|
nrg1
|
comt
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NAC | VH | mPFC | NAC | VH | mPFC | NAC | VH | mPFC | NAC | VH | mPFC | Blood | ||
| csnkle | NAC | – | ||||||||||||
| VH | 0.23 | – | ||||||||||||
| mPFC | 0.39* | 0.49** | – | |||||||||||
| grid2 | NAC | 0.94**** | 0.31 | 0.37* | – | |||||||||
| VH | 0.08 | 0.53** | 0.19 | 0.03 | – | |||||||||
| mPFC | 0.39* | 0.50** | 0.89**** | 0.42* | 0.25 | – | ||||||||
| nrg1 | NAC | 0.84**** | 0.30 | 0.33 | 0.88**** | 0.15 | 0.41 | – | ||||||
| VH | 0.14 | 0.82**** | 0.21 | 0.01 | 0.41* | 0.21 | 0.01 | – | ||||||
| mPFC | 0.36* | 0.61*** | 0.86**** | 0.43* | 0.23 | 0.83**** | 0.45** | 0.41* | – | |||||
| comt | NAC | 0.93**** | 0.17 | 0.30 | 0.93**** | 0.04 | 0.37* | 0.87**** | −0.17 | 0.31 | – | |||
| VH | 0.50** | 0.88**** | 0.55*** | 0.57*** | 0.47** | 0.59*** | 0.58*** | 0.53** | 0.66**** | 0.48** | – | |||
| mPFC | 0.40* | 0.60*** | 0.85**** | 0.42* | 0.15 | 0.81**** | 0.41* | 0.39* | 0.80**** | 0.36* | 0.66**** | – | ||
| Blood | 0.10 | 0.48** | 0.01 | 0.22 | 0.09 | 0.06 | 0.28 | 0.62 | 0.29 | 0.09 | 0.31 | 0.08 | – | |
| AMPH effect | ||||||||||||||
| 30 ms | 0.03 | −0.26 | 0.22 | −0.06 | −0.20 | 0.09 | −0.19 | −0.47** | −0.04 | 0.05 | −0.15 | 0.09 | −0.62**** | |
| 120 ms | −0.28 | −0.08 | 0.06 | −0.33 | 0.01 | −0.23 | −0.38* | −0.03 | −0.08 | −0.28 | −0.23 | 0.01 | −0.25 | |
| PA | −0.11 | 0.22 | −0.09 | −0.06 | 0.15 | −0.07 | 0.03 | 0.48** | 0.13 | −0.10 | 0.07 | 0.03 | 0.54** | |
p<0.05
p<0.01
p<0.001
p<0.0001