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. 2016 Dec 31;9(2):154–162. doi: 10.14740/jocmr2875w

Figure 1.

Figure 1

Effect of ipragliflozin on efficacy parameters at week 24 in all patients (n = 50), classified according to estimated glomerular filtration rate (eGFR) at baseline into three groups: eGFR ≥ 90 (circles; n = 20), eGFR ≥ 60 to < 90 (triangles; n = 22), and eGFR < 60 (squares; n = 8). (a) Change from baseline in glycated hemoglobin (HbA1c) to week 24 after starting ipragliflozin administration. (b) Change from baseline in body weight. (c) Change from baseline in eGFR. (d) Change from baseline in urinary albumin-to-creatinine ratio (UACR) at week 24. Data are means ± standard deviation (SD) or medians with the interquartile range (IQR). *P < 0.05, **P < 0.01 versus baseline by the paired t-test. For the UACR, the Wilcoxon signed-rank test was used to evaluate changes between the baseline and week 24. Error bars show SDs or IQRs.