. Author manuscript; available in PMC: 2017 Jan 5.

Published in final edited form as: Catal Sci Technol. 2016 Mar 24;6(14):5304–5310. doi: 10.1039/C6CY00457A

Table 1.

Reaction optimization^a


Entry	Additive	OR′	R	Yield [%]
1	—	OAc	Ac	11
2	—	OAc	COCF₃	21
3	—	OAc	Ts	13
4	—	OTs	Ts	10
5	—	O₂CCF₃	COCF₃	22
6	1 equiv. AcOH	OAc	Ac	29
7	5 mol% AgOAc	OAc	Ac	27
8	1 equiv. AcOH	O₂CCF₃	COCF₃	17
9	5 mol% AgOAc	O₂CCF₃	COCF₃	22
10	1 equiv. AcOH^b	OAc	Ac	0

Conditions: benzene (0.50 mL, 5.6 mmol, 40 equiv.), Pd(OAc)₂ (3.1 mg, 14 μmol, 10 mol%), 1 (2.5 mg, 14 μmol, 10 mol%), RNH–OR′ (140 μmol, 1.0 equiv.), 100 °C, 24 h.

No Pd catalyst.