Table 4.

Estimated Sample Sizes by Baseline 6MWD Level Based on Hospitalized COPD Exacerbations or Death up to 12 Months of Follow-up

6MWD, m	Group Sample Size by Hazard Ratio for Hospitalization			Group Sample Size by Hazard Ratio for Death
	0.6	0.7	0.8	0.6	0.7	0.8
<250	318	612	1,478	500	952	2,288
<300	348	666	1,606	618	1,176	2,820
<350	386	738	1,780	718	1,364	3,268
<400	428	818	1,968	980	1,860	4,450
<450	474	904	2,174	1,066	2,022	4,836
No threshold	520	992	2,386	1,226	2,324	5,552

Definition of abbreviations: 6MWD = 6-minute-walk distance; COPD = chronic obstructive pulmonary disease.