Table 2.

Omalizumab Is Associated with Reduced Acute Exacerbation Severity

Outcomes	Univariate Analysis			Multivariate Analysis
	Coef or OR*	95% CI	P Value	Coef or OR	95% CI	P Value
Continuous
Exacerbation MPIS	−3.32	−4.82 to −1.82	<0.001	−2.83	−4.01 to −1.66	<0.001
Exacerbation PEF%	16.49	8.56 to 24.42	<0.001	13.72	6.99 to 20.45	<0.001
Time to albuterol every 2 h	−15.85	−24.28 to −7.43	<0.001	−16.59	−24.05 to −9.13	<0.001
Hospital length of stay	−24.01	−37.32 to −10.70	0.001	−24.57	−36.17 to −12.98	<0.001
Dichotomous
Hospital admission	0.38	0.16 to 0.88	0.024	0.30	0.11 to 0.83	0.021
ICU admission	0.31	0.12 to 0.82	0.018	0.24	0.08 to 0.75	0.014
Supplemental O2	0.26	0.09 to 0.74	0.011	0.24	0.07 to 0.79	0.019
Noninvasive PPV	0.17	0.04 to 0.74	0.035	0.21	0.04 to 1.01	0.052

Definition of abbreviations: CI = confidence interval; Coef = coefficient; ICU = intensive care unit; MPIS = Modified Pulmonary Index Score; OR = odds ratio; PEF = peak expiratory flow; PPV = positive pressure ventilation.

^*Coefficient for continous variables and OR for dichotomous variables.