Table 2.
SNPs with E-07 or Lower Level of Significance were evaluated for their proximity to known genes and possible clues to their biological significance
| Recipient (R) or Donor (D) Genome |
dbSNP ID | Chromosome | Position | Gene Region | Gene ID | Observed MAFa |
Minor Allele Frequencyb |
p-value |
|---|---|---|---|---|---|---|---|---|
| R | rs1389663 | 3 | 22331934 | ZNF385D: zinc finger protein 385D | 79750 | 0.391 | 0.429 | 7.42E-10 |
| R | rs9277378 | 6 | 33158257 | HLA-DPB1 | 3115 | NA | 0.273 | 1.58E-09 |
| D | rs13221852 | 7 | 3455665 | SDK1: sidekick cell adhesion molecule 1 |
221935 | 0.4856 | 0.495 | 1.56E-08 |
| R | rs16866061 | 2 | 225148088 | CUL3: cullin3 | 8452 | 0.326 | 0.333 | 2.47E-08 |
| R | rs12030196 | 1 | 59255908 | - | - | NA | 0.232 | 3.42E-08 |
| R | rs11023435 | 11 | 15084922 | - | - | 0.164 | 0.460 | 4.08E-08 |
| D | rs529967 | 3 | 125649193 | KALRN: kalirin, Rho guanine nucleotide exchange factor kinase |
8997 | 0.406 | 0.298 | 4.12E-08 |
| R | rs465530 | 12 | 63617033 | FLJ41278: uncharacterized LOC400046 |
400046 | 0.437 | 0.490 | 4.20E-08 |
| R | rs7234719 | 18 | 26521532 | - | - | 0.336 | 0.278 | 6.51E-08 |
| R | rs1147805 | 9 | 25764342 | - | - | 0.487 | 0.439 | 8.71E-08 |
| R | rs4981053 | 14 | 19592561 | OR4U1P: olfactory receptor, family 4, subfamily U, member 1 pseudogene |
390434 | 0.472 | 0.470 | 1.22E-07 |
| R | rs12641631 | 4 | 154884729 | RNF175: ring finger protein 175 | 285533 | 0.193 | 0.207 | 1.39E-07 |
| R | rs6651135 | 7 | 53258364 | HAUS6P1: HAUS augmin like complex subunit 6 pseudogene 1 |
653175 | 0.173 | 0.136 | 1.55E-07 |
| R | rs7192392 | 16 | 77489879 | WWOX: WW domain containing oxidoreductase |
51741 | NA | 0.394 | 1.75E-07 |
| R | rs11096855 | 4 | 36671033 | - | - | 0.178 | 0.172 | 1.87E-07 |
| R | rs10869777 | 9 | 78238977 | GCNT1: glucosaminyl (N-acetyl) transferase 1, core 2 |
2650 | 0.430 | 0.490 | 2.10E-07 |
| R | rs11764561 | 7 | 155714863 | - | - | 0.218 | 0.232 | 2.30E-07 |
| R | rs12502114 | 4 | 182878208 | - | - | NA | 0.394 | 2.89E-07 |
| R | rs10090774 | 8 | 141895921 | PTK2: protein tyrosine kinase 2 | 5747 | 0.449 | 0.429 | 3.66E-07 |
| R | rs1360141 | 9 | 73481836 | - | - | 0.403 | 0.359 | 7.48E-07 |
| D | rs1387416 | 6 | 75023776 | LOC101928516: uncharacterized LOC101928516 |
101928516 | 0.449 | 0.465 | 8.38E-07 |
| R | rs6547818 | 2 | 21743084 | - | - | 0.447 | 0.444 | 9.69E-07 |
a
Observed minor allele frequencies (MAF) from individual SNP genotyping. NA indicates not available
b
From The 1000 Genomes Project - Utah residents with ancestry from northern and western Europe (CEPH) http://browser.1000genomes.org