Table 3.
Linkage Disequilibrium between Current Study SNPs, and between Current Study and Selected Published HLA-DP Region SNPsa
| Gene Region |
Current Study |
Proxyb | Distance, bp |
D’ | r2 | Minor Allele Frequencyc |
|---|---|---|---|---|---|---|
| HLA-DPB1 | rs9277378 | 0.273 | ||||
| rs9277534 (9,12,13) |
4528 | 1 | 0.96 | 0.283 | ||
| rs9277535 (9,12) |
4582 | 0.96 | 0.78 | 0.242 | ||
| rs9277542 (11) |
4968 | 1 | 0.96 | 0.278 | ||
| rs2281389 (14) |
9517 | 1 | 0.532 | 0.136 | ||
| HLA-DPB1 | rs9277542 | |||||
| rs9277534 (9,12,13) |
440 | 1 | 1.00 | 0.283 | ||
| rs9277535 (9,12) |
386 | 1 | 0.82 | 0.242 | ||
| rs9277378 (current study) |
4968 | 1 | 0.96 | 0.273 | ||
| rs2281389 (14) |
4549 | 1 | 0.512 | 0.136 | ||
| HLA-DPA1 | rs9277341 | 0.298 | ||||
| rs3077 (12) |
6603 | 1 | 0.48 | 0.182 |
a
Johnson, A. D. et al. SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics, 2008 24(24):2938
b
Referenced publications are provided in parentheses
c
From The 1000 Genomes Project - Utah residents with ancestry from northern and western Europe (CEPH)