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. 2016 Sep 19;60:71–83. doi: 10.1016/j.bbi.2016.09.022

Fig. 2.

Fig. 2

B cell accumulation within the brain peaks by day 7 p.i. Numbers of total CD19+, IgDintIgM+, IgDIgM+, and IgDIgM B cells determined by flow cytometry within the CLN (A) and brain (B) in naïve and infected mice at day 7, 14, and 21 p.i. Data are expressed as the mean number ± SEM and represent 3–4 independent experiments each comprising 3–6 pooled brains or CLNs per time point. B cells within brains of naïve mice were not detectable (ND). Significant differences between time points are denoted by ∗ (p < 0.05) and ∗∗ (p < 0.01).