Table 2.

Biomarker Levels in Participants With Acute HIV Infection

Biomarker	Participants With Acute HIV Infection by 4thG Stage and Week of ART
	All Stages						4thG1						4thG2						4thG3
ARTa	0 (n = 75)	2	12	24	48	96	0 (n = 14)	2	12	24	48	96	0 (n = 20)	2	12	24	48	96	0 (n = 41)	2	12	24	48	96
CRP, µg/mL	1.34	0.77	0.51	0.45	0.34	0.49	0.81	1.25	0.51	0.55	0.52	0.51	3.15	0.69	0.29	0.28	0.25	0.35	1.34	0.52	0.59	0.48	0.38	0.49
TNF, pg/mL	1.72	NA	NA	1.46	3.52	1.50	1.01	NA	NA	1.65	0.96	1.21	2.10	NA	NA	1.69	2.89	2.05	1.84	NA	NA	1.24	3.95	1.50
IL-6, pg/mL	0.60	NA	NA	0.40	0.78	0.54	0.31	NA	NA	0.39	0.4	0.29	0.84	NA	NA	0.45	1.14	0.75	0.60	NA	NA	0.34	0.77	0.50
sIL-6R, ng/mL	17.0	NA	NA	14.1	NA	13.3	13.3	NA	NA	13.2	NA	13.9	15.7	NA	NA	14.1	NA	11.7	18.6	NA	NA	14.1	NA	13.6
sgp130, ng/mL	90	NA	NA	114	NA	104	105	NA	NA	114	NA	113	92	NA	NA	111	NA	102	85	NA	NA	114	NA	104
I-FABP, pg/mL	1004	2661	2702	2009	2869	2528	812	2698	2441	1426	2921	2979	1041	2607	3492	2792	3173	3715	1044	2668	2702	1734	2642	2254
sCD14, µg/mL	1.51	1.32	1.18	1.16	1.04	1.15	1.20	1.57	1.20	1.20	0.98	1.24	1.57	1.32	1.06	1.06	1.06	1.17	1.57	1.30	1.19	1.22	1.01	1.11
D-dimer, µg/mL	0.28	0.23	0.15	0.15	0.17	0.18	0.17	0.32	0.15	0.17	0.19	0.25	0.30	0.34	0.17	0.19	0.16	0.13	0.33	0.22	0.13	0.15	0.16	0.18
HA, ng/mL	18.4	10.2	12.5	18.5	15.7	12.2	12.5	14.7	11.3	15.9	18.1	11.8	15.3	9.0	15.9	21.4	17.7	18.5	23.7	9.0	12.0	17.6	15.6	12.1

Abbreviations: 4thG, fourth-generation; 4thG1, 4thG stage 1; 4thG2, 4thG stage 2; 4thG3, 4thG stage 3; ART, antiretroviral therapy; CRP, C-reactive protein; D-dimer, coagulation cascade activation; HA, hyaluronic acid; HIV, human immunodeficiency virus; I-FABP, intestinal fatty acid binding protein; IL-6, interleukin 6; NA, not available; sCD14, soluble CD14; sgp130, soluble gp130; sIL-6R, soluble IL-6 receptor; TNF, tumor necrosis factor.

^a All biomarker.