Table 3.

Cox regression analysis of overall survival (Cohort 2)

Prognostic factor	Univariate			Multivariatea
	HR	(95% CI)	P-value	HR	(95% CI)	P-value
CUBN (pos. vs. neg., ref)	0.411	0.263–0.641	<0.001	0.382	0.203–0.719	0.003
T-Stage (T3-T4 vs. T1-T2, ref)	1.897	1.002–3.593	0.049	1.689	0.746–3.825	0.209
Fuhrman Grade (3–4 vs. 1–2, ref)	1.822	1.059–3.136	0.030	1.217	0.665–2.226	0.524
Nodal Status (pos. vs. neg., ref)	4.208	2.397–7.386	<0.001	4.041	1.840–8.874	0.001

HR hazard ratio, CI confidence interval

^aAdjusted for all other variables; pos., positive; neg., negative; ref, referent group