Table 2.
N (%) of individuals with each somatic illness by group (case = 850; control = 8,500) and results of conditional logistic regressions evaluating the association of binge‐eating disorder (BED) with each somatic illness [OR (95% CI)], and adjusted for lifetime psychiatric comorbidity [AOR (95% CI)]
| Somatic Illness Category | BED (Cases) N (%) | Controls N (%) | OR (95% CI) | p Values | AOR (95% CI) | p Values |
|---|---|---|---|---|---|---|
| Neurologic diseases | 68 (8.0) | 411 (4.8) | 1.7 (1.3; 2.2) | 0.0002 | 1.1 (0.8; 1.5) | 0.38 |
| Infectious and parasitic diseases | 181 (21.3) | 1394 (16.4) | 1.4 (1.2; 1.6) | 0.0005 | 1.1 (0.9; 1.4) | 0.20 |
| Immune system disorders | <4 | 20 (0.2) | NAa | — | NAa | — |
| Respiratory diseases | 254 (29.9) | 1941 (22.8) | 1.4 (1.2; 1.7) | 0.0001 | 1.3 (1.1; 1.5) | 0.004 |
| Gastrointestinal disorders | 120 (14.1) | 903 (10.6) | 1.4 (1.1; 1.7) | 0.0053b | 1.1 (0.9; 1.4) | 0.82b |
| Skin and subcutaneous tissue disorders | 133 (15.7) | 926 (10.9) | 1.5 (1.2; 1.8) | 0.0001 | 1.3 (1.1; 1.6) | 0.014 |
| Musculoskeletal system and connective tissues diseases | 178 (20.9) | 1156 (13.6) | 1.7 (1.4; 2.0) | 0.0002b | 1.5 (1.3; 1.9) | 0.0002b |
| Genitourinary system diseases | 39 (4.6) | 285 (3.4) | 1.4 (1.0; 2.0) | 0.09 | 1.2 (0.8; 1.7) | 0.42 |
| Circulatory system diseases | 42 (4.9) | 217 (2.6) | 1.9 (1.3; 2.7) | 0.0006b | 1.6 (1.1; 2.4) | 0.02b |
| Endocrine system diseases (excluding diabetes mellitus) | 84 (9.9) | 341 (4.0) | 1.8 (1.3; 2.4) | 0.0003 | 1.5 (1.0; 2.0) | 0.04b |
| Diabetes mellitus | 40 (4.7) | 74 (0.9) | 5.7 (3.8; 8.7) | 0.0002b | 5.8 (3.6; 9.4) | 0.0002b |
| Congenital malformations | 37 (4.4) | 327 (3.9) | 1.1 (0.8; 1.6) | 0.50 | 1.1 (0.7; 1.5) | 0.77 |
| Injury, poisoning and external causes of morbidity and mortality (excluding suicide) | 402 (47.3) | 3154 (37.1) | 1.5 (1.3; 1.8) | 0.0001 | 1.1 (1.0; 1.3) | 0.15 |
a
Cell size < 5, analysis not applied. Psychiatric comorbidity refers to any lifetime psychiatric disorder or suicide‐related behavior recorded in the National Patient Register. Controls were matched to cases on sex and year, month, and county of birth. AOR = adjusted odds ratio, CI = confidence interval, OR = odds ratio.
b
p values adjusted by the method of false discovery rate.