Table 2.
Metabolite COVs for Voxels Containing Spectra That Meet Overall Water Line Width Criteriaa
| 0‐0.1 ppm | ||||||||
|---|---|---|---|---|---|---|---|---|
| TE = 35ms | TE = 80ms | TE = 144ms | Echo time comparison | |||||
| Line width | COV % | COV % | COV % | ANOVA | ||||
| Metabolite | Si.BL | Ex.BL | Si.BL | Ex.BL | Si.BL | Ex.BL | Si.BL | Ex.BL |
| tNAA††¥¥ | 9.99 | 7.56 | 6.03 | 5.35 | 12.31 | 7.81 | <0.00001 | <0.00001 |
| tCr | 10.13 | 9.25 | 7.18 | 7.22 | 11.56 | 10.91 | <0.00001 | <0.00001 |
| tCho | 9.00 | 9.40 | 8.16 | 8.10 | 9.78 | 9.61 | 0.1209 | 0.1027 |
| Glu†† | 20.35 | 16.33 | 22.36 | 22.82 | 45.96 | 47.57 | <0.00001 | <0.00001 |
| Gln¥ | 83.80 | 88.85 | 56.22 | 60.19 | 47.37 | 53.22 | <0.00001 | <0.00001 |
| Glx††¥ | 24.85 | 19.95 | 22.81 | 23.25 | 22.49 | 25.39 | 0.1525 | 0.0001 |
| Ins | 15.36 | 15.36 | 16.97 | 17.87 | 34.46 | 33.84 | <0.00001 | <0.00001 |
| Glth† | 48.43 | 68.14 | 28.33 | 27.67 | 69.06 | 68.39 | <0.00001 | <0.00001 |
| Tau†† | 127.97 | 89.93 | 70.56 | 70.56 | 70.71 | 66.25 | <0.00001 | <0.00001 |
a
Metabolite COVs for TE = 35, 80, and 144 ms for voxels containing spectra that meet the overall water line width criteria of between 0 and 0.1 ppm showing significant (P < 0.05) differences from an unpaired t‐test between Si.BL and Ex.BL for TE = 35 ms (†), TE = 80 ms (‡), and TE = 144 ms (¥). Significances of P < 0.01 are denoted as: TE = 35 ms (††), TE = 80 ms (‡‡), and TE = 144 ms (¥¥).