Table 2. Molecules Predicted to be Suppressed by TGF-β3.
TBX2 | FOXM1 | CCND1 | E2F3 | MYC |
MITF | SREBF1 | SREBF2 | FOXO1 | E2F1 |
E2F2 | ATF4 | SOX2 | TFDP1 | ARNTL |
IRF5 | IRF3 | REL | TP63 | MED1 |
MBD2 | SATB1 | USF1 | HMGB1 | IRF1 |
MYBL2 | NKX2-3 | PPARGC1B | KLF15 | MKL2 |
MAX | SIRT2 | TLX1 | HOXB4 |
Upstream Regulator Analysis in IPA was used to predict molecules inhibited by TGF-β3[31]. Transcription regulators with activation z-scores less than 2 (i.e. whose function was predicted to be inhibited by TGF-β3) are shown.