Figure 1.

Schematic of study design. After screening to ensure that all study criteria were met, subjects were randomized to receive a single dose of 0.3 U/kg IGlar or 0.3 U/kg LY IGlar on day 1 of period 1, followed by a 42‐hour euglycaemic clamp procedure. Following a washout period of 7‐21 days, subjects received a single dose of the other insulin glargine on day 1 of period 2, followed by a 42‐hour euglycaemic clamp procedure. Subjects returned for a follow‐up visit 7‐14 days after the second clamp procedure.