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. 2016 Aug 26;12(12):3072–3078. doi: 10.1080/21645515.2016.1212143

Table 5.

Solicited reactions with 7 d after any injection.

  IIV4
Pooled IIV3
Event n/N % (95% CI) n/N % (95% CI)
Injection-site reaction 550/882 62.4 (59.1, 65.6) 221/354 62.4 (57.2, 67.5)
Pain 498/882 56.5 (53.1, 59.8) 196/354 55.4 (50.0, 60.6)
Erythema 180/882 20.4 (17.8, 23.2) 79/354 22.3 (18.1, 27.0)
Swelling 181/882 20.5 (17.9, 23.3) 71/354 20.1 (16.0, 24.6)
Induration 145/882 16.4 (14.1, 19.1) 50/354 14.1 (10.7, 18.2)
Ecchymosis 51/882 5.8 (4.3, 7.5) 22/354 6.2 (3.9, 9.3)
Systemic reaction 431/882 48.9 (45.5, 52.2) 161/354 45.5 (40.2, 50.8)
Fever 74/879 8.4 (6.7, 10.5) 23/353 6.5 (4.2, 9.6)
Headache 227/882 25.7 (22.9, 28.8) 68/354 19.2 (15.2, 23.7)
Malaise 271/882 30.7 (27.7, 33.9) 100/354 28.2 (23.6, 33.2)
Myalgia 251/882 28.5 (25.5, 31.6) 95/354 26.8 (22.3, 31.8)
Shivering 99/882 11.2 (9.2, 13.5) 32/354 9.0 (6.3, 12.5)

Values are for the safety analysis set. CI, confidence interval