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. 2017 Jan 4;13(1):e1006096. doi: 10.1371/journal.ppat.1006096

Fig 2. Drug susceptibility of A. fumigatus strains linked to modifications of the atrR and srbA genes.

Fig 2

(A) Antifungal drug susceptibility test by paper-disc diffusion assay. GMM plates containing conidia of each strain were prepared. A paper-disc was placed on center of the plate, and 10 μl of drug solution indicated was dropped on it (fluconazole (FLCZ): 10 mg/mL; MCZ: 10 mg/mL; amphotericin B (AMPH): 0.25 mg/mL; micafungin (MCFG): 0.02 mg/mL). The plates were incubated for 48 h before photographed. (B) Inhibition test for colony growth by antifungal drugs. The conidia of each strain were center-inoculated onto GMM plates containing indicated concentrations of itraconazole (ITCZ) or MCZ. The plates were incubated for 70 h. The colony diameter was measured in triplicates, and the mean values for plates with drugs were compared with those without drugs. The percentage of growth was plotted in the graphs.