Fig. 5.
Lenalidomide augments cell death in vitro with TNF-α but not with FasL. (A) MBT-2 cells were treated as indicated in the figure; 24 hours after treatment, the cells were imaged. Len = lenalidomide, TNF-α and FasL concentrations were 17 ng/ml. (B) The cell death was confirmed by chromatin condensation (because of caspase-3 activation) by staining the cells using live stain Hoechst-33,342. Note the chromatin condensation (arrow heads) in TNF-α treated conditions but not in FasL treated conditions. (Color version of figure is available online.)