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TNF-α but not FasL induce apoptosis and cell proliferation events in vitro. MBT-2 cells were treated as indicated in figures and were lysed and subjected to immunoblotting as described in the Materials and Methods section. (A) Western analysis of apoptotic regulators BCLXL and Caspase-3. TNF-α, but not FasL is able to induce active caspase-3 either alone or in combination with lenalidomide. (B) Western analysis of cell cycle regulators p27 and cyclin-D1.
