Figure 5.
MEG data epoched around movement completion (t 0 = finger replaced). A: TFR (averaged across healthy controls only) from motor cortex ROIs relative to effector limb. Post Movement Beta Rebound (PMBR, in red) is predominantly contralateral in healthy controls. B,C: Beta‐band power (relative to baseline) within contralateral motor cortex ROI; group comparison. Black bar = timespan of significant group difference via cluster permutation testing, P < 0.05. Vertical lines denote appearance of Go target, timing of response initiation and completion. D: ALS patients demonstrate lower beta power in early transition to PMBR [t 0 + 500 ms: t 0 + 700 ms]. t‐stats in blue, motor cortex mask used for statistics in green. E: Beta‐band power lateralization evolves over time around a response, PLS patients show a diminished DoL during PMBR (black bar, P < 0.05). F: PMBR DoL appraised in whole‐brain data [t 0 + 1 s: t 0 + 2.5 s]. PLS patients again show significantly reduced DoL. t‐stats in ROY‐BIG‐BL. [Color figure can be viewed at http://wileyonlinelibrary.com.]