Table 2.
Comprehensive comparisons of non-genetic demographic predictors of CHF
| Clinical Trial | Samples with clinical data available | |||||
|---|---|---|---|---|---|---|
| All | AA | EA | ||||
| Age | BSA | Age | BSA | Age | BSA | |
|
E5103* (genotyped) N=3394 (68 cases) AA=386 (13 cases) EA=2525 (51 cases) Others=484 (4 cases) |
0.009 | 0.10 | 0.76 | 0.01 | 0.002 | 0.79 |
|
E1199 (Parent trial) N=4735 (71 cases) AA=401 (11 cases) EA=4042 (58 cases) Others=292 (2 cases) |
0.005 | 0.04 | 0.62 | 0.10 | 0.005 | 0.48 |
|
E1199 (genotyped) N=2906 (47 cases) AA=267(38 cases) EA=2616 (7 cases) Others=23 (2 cases) |
0.044 | 0.07 | 0.50 | 0.07 | 0.08 | 0.61 |
|
BEATRICE* (genotyped) N=828 (24 cases) AA=31 (1 case) EA=705 (21 cases) Others=92 (2 cases) |
0.774 | 0.91 | 0.99 | 0.99 | 0.87 | 0.72 |
*
Clinical data was only available for those patients who had companion DNA samples
AA=African American; EA=European American; BSA=Body Surface Area